Before being tested in animals or humans, most cancer drugs are evaluated in tumor cells grown in a lab dish. However, in recent years, there has been a
A Belgian team of computational biologists led by Stein Aerts (VIB-KU Leuven) has developed a new bioinformatics method called cisTopic. Inspired by text-mining methods, cisTopic helps scientists to
When scientists attempt to slip big molecules, like the Cas9 enzyme that is key to CRISPR gene editing, into cells, things can get messy. One popular technique, bulk
Cancer cells consume sugar at a higher rate than healthy cells, but they’re also hungry for amino acids, the building blocks of proteins and other biomolecules. Researchers at
Researchers from the Institute of Neurosciences of the University of Barcelona (NeuroUB) and the Bellvitge Biomedical Research Institute (IDIBELL) and from the New York University (USA), studied the
Buried deep within the dazzlingly intricate machinery of the human cell could lie a key to treating a range of deadly cancers, according to a team of scientists
As new technology allows researchers to plunge deeper into the genome and exome, a new class of RNA called circular RNA may play an intriguing role. Researchers at
DNA replication is more prone to errors at times of stress leading to mutations that could cause disease. Cells go to great lengths to keep their genomes intact.
Nearly two decades after a class of once-promising cancer drugs called MMP inhibitors mysteriously failed in clinical trials, scientists think they may have an explanation for what went
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